Even more alarming is the projection that total deaths caused by diabetes is most likely to increase two folds in the next 10 years. Some of these I know more about than others, so let me Individuals suffering from it also complain of increased fatigue, weakness, headache, and muscle spasms. Mucopolysaccharidosis VI is a genetic disease that affects about 1 in 300,000 births. There is no cure. Symptoms: This disease is characterized by vomiting, seizures, mental retardation, deafness, and blindness. Alagille syndrome is a rare genetic disorder that affects the liver, kidney, heart, and other organs of the body. It is also advisable to avoid diets rich in tyrosine and phenylalanine. So far there has not been any major Ebola outbreak elsewhere in the world, which is indeed fortunate since a cure to the disease is yet to be found. The gene that causes ossification is normally deactivated once the fetus’ bones are completely formed in the womb, but in patients with FOP, the gene keeps on working. New infections continue to emerge today, while many of the old plagues are with us still. This results into complete ossification of damaged tendons, ligaments and muscles; meaning all the damaged connective tissues gets regrown into bones, slowly imprisoning the sufferers into their own skeletons. Treatment: There is no cure for this condition but it can be partially treated. To worsen the matter, the World Health Organization projects that without immediate action, the global number of deaths from cancer will increase by nearly 80% by 2030, with most occurring in low- and middle-income countries. But an acute treatment to cure them does not exist. It may occur as an isolated abnormality (no additional symptoms) or be associated with a specific genetic disorder (such as Kallmann syndrome or congenital insensitivity to pain). In 2008 alone, there were 7.6 million deaths globally because of cancer, accounting for 13% of the total deaths that year. An estimated 300 million people worldwide suffer from asthma, with 250,000 annual deaths attributed to the disease. While the patients suffer from unbelievable highs in pulse and blood pressure, excessive sweating and an eventual loss of coordination and other gross motor skills (including speech), the thinking portions remain intact, even as the rest of the body deteriorates. These are areas of brain control movement. In people affected by this syndrome, the bones of the skull fuse prematurely, a condition called craniosynostosis, while the brain keeps developing inside the abnormal skull causing pressure on the skull and face, resulting in its distortion. Carpenter syndrome is a rare congenital disorder characterized by malformed head, face, fingers, and toes due to premature fusion of bones. It is estimated to affect 1 in 1000,000 individuals. It results in distortion in the shape of skull and face, and sometimes, the hands and feet are webbed. We also use third-party cookies that help us analyze and understand how you use this website. Huntington’s disease is an autosomal dominant genetic disorder and is more prevalent in the mid-adult life. Bardet-Biedl syndrome is a rare genetic disorder affecting multiple organs. It affects around 1 in 70,000 newborns. Treatment: There is no cure for this syndrome; however, corrective surgery aimed at the functioning of heart, liver, and kidney helps to some extent. Treatment: There is no cure for this condition. Genetic diseases and disorders are a major challenge for medical researchers all over the world. But everything else about it is wildly unpredictable. Treatment: Symptoms of epileptic seizures can be treated by surgically removing the tubers that are responsible for epilepsy. “any disease or condition that affects less than 200,000 persons in the United States, or about 1 in 1500.”. A genetic test for LMNA mutation can confirm if an individual has progeria. Since its inception, almost 70 million people have been infected with the HIV virus and about 35 million people have died of AIDS. Congenital anosmia is a condition in which people are born with a lifelong inability to smell. Of course, we should want to give our kids the life they were supposed to have. A few decades back, Diabetes was thought of a rich man’s disease, the number of people with diabetes constricted to the upper echelon of society. Even though a baby with this genetic mutation is born normal and healthy, the symptoms start emerging once the child reaches the age of 18-24 months. Importantly, it may also red-flag treatments likely to cause adverse reactions. This disease usually appears in the later life and but its severity grows with extreme rapidness.eval(ez_write_tag([[580,400],'elist10_com-banner-1','ezslot_0',107,'0','0'])); CJD is thought to be caused by a protien called a prion. It affects 1 in 140,000 to 1 in 160,000 newborns. Grievous genetic diseases caused by point mutations are especially frustrating, because we often know the exact single-letter change that causes the disease and, in theory, could cure the disease. Individuals can be affected by this syndrome at any time of their life; however, it is more prevalent in the age group of 40-50 years. Joubert’s syndrome is a rare autosomal recessive genetic disorder of the brain. The symptoms are generally evident in the first few weeks of life. Formerly known as Fahr’s syndrome, it is a rare genetically dominant disorder. It is genetic, and no known cure exists. Batten disease is characterized by a buildup of pigments called lipofuscins in the body cells. But along with them, we have also recorded the emergence of new devastating infections and dangerous diseases. 10. Indeed, one of the first and most advanced CRISPR clinical trials, which is currently running in China, is testing the potential of the gene editing tool to treat patients with advanced cancer of the esophagus. Genome sequencing has the potential to improve the diagnosis of conditions caused by changes in the DNA and indicate what treatments may be most effective. Symptoms: Symptoms include yellowish tinge on the skin and the whites of the eyes, accumulation of cholesterol beneath the skin, itching, etc. Treatment: There is no cure for this disorder. Treatment generally involves management of seizures and supporting the affected individuals through the delay in development. Also advisable to avoid diets rich in tyrosine and phenylalanine medical researchers all over the world number of staged to! 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